Research primates may undergo surgical procedures making effective pain management essential to ensure good animal welfare and unbiased scientific data.Adequate pain mitigation is dependent on whether veterinarians, technicians, researchers, and caregivers can recognize and assess pain, as well as the availability of efficacious therapeutics.A surv

OBJECTIVES/GOALS: Utilize polymer-based fiber scaffolds and machine learning methods applied to patient biomarker data to enhance and personalize T cell expansion and production for T cell therapy in chronic lymphocytic leukemia.METHODS/STUDY POPULATION: Scaffolds are 1) generated from a co-polymer blend of PDMS and PCL with controlled fiber diamet

Gap junctions are intercellular connections that enable direct communication Flea between neighboring cells.They are important in tissue homeostasis, cell growth, and differentiation.They are composed of connexin proteins, of which the most common and most studied is connexin 43.The role of connexin 43 in the development and progression of tumors i

Lobular carcinoma (LC) presents unique diagnostic challenges due to its subtle imaging characteristics and asymptomatic presentation, often leading to delays in diagnosis and treatment.This mini-review critically examines both traditional and advanced imaging modalities used to detect and manage LC, including mammography, ultrasound, digital breast